Projects & Grants

Internal Grant Competition DGC
START-UP grant





Leishmania development in phlebotomine sand flies and transmission to the vertebrates: the role of leishmaniaviruses and RNA interference
Project Id26-20420S
Main solverprof. MSc. Vjačeslav Jurčenko, Ph.D.
Period1/2026 - 12/2028
ProviderStandardní projekt GA ČR
Statesolved
AnotationUnderstanding the molecular aspects of Leishmania-sand fly interactions is highly important for the effective control and prevention of the disease. In the proposed study, we will assess, for the first time, the role of RNA viruses and RNAi mechanisms in regulating Leishmania development in sand flies and their subsequent transmission to the vertebrate hosts. In addition, and, again, for the first time, we will use high-throughput sequencing to link the observed phenotypes to the differences in the insect immune responses.
Total Costs11 751 000 CZK