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The effect of postoperative flexible bronchoscopy on reducing pulmonary complications in the surgical treatment of lung cancer
Project IdSGS04/LF/2026
Main solverMUDr. Paula Dzurňáková
Period1/2026 - 12/2026
ProviderSpecifický VŠ výzkum
Statesolved
AnotationAccording to the Czech Oncological Society of the Czech Medical Association of J. E. Purkyně, approximately 6,500 new cases of malignant lung tumors are diagnosed in the Czech Republic every year. It is the third most common malignant tumor disease, and its incidence is constantly increasing over time. Between 10 and 17% of patients with newly diagnosed lung cancer undergo primary radical surgery. In addition to the basic oncological diagnosis, patients indicated for lung surgery for tumors also have compromised lung function due to many other pre-existing factors, the most common of which are smoking, chronic obstructive pulmonary disease, cardiovascular disease, diabetes, obesity, malnutrition, and sarcopenia. During surgery, a number of pathophysiological changes occur in the lungs, resulting in further deterioration of lung function. After lung surgery, patients experience varying lengths of time of pharmacological sedation, the effects of muscle relaxation, post-intubation slowed mucociliary transport, and pain. All of these factors are ultimately responsible for impaired mucus expectoration and its retention in the airways, the formation of mucus plugs, which directly contributes to the occurrence of early postoperative pulmonary complications ? pneumonia, atelectasis, respiratory failure, etc. The literature reports the incidence of these complications in 6-10% of recorded surgical procedures. At University hospital in Ostrava, the incidence of these complications is at the upper end of the global range, between 10% and 11%. In general, the most effective way to reduce complications is to prevent them. Flexible fiberoptic bronchoscopy is a modern, effective, and accessible method of preventing the retention of pathological secretions in the airways. This intervention can also be performed in patients with malignant lung tumors after radical surgery, regardless of age, gender, and comorbidities.
Total Costs239 800 CZK