Projects & Grants

Internal Grant Competition DGC
START-UP grant

Bone Marrow Microenvironment in Multiple Myeloma: Application of 2D and 3D in vitro models using patient's specific IPSCs derived Mesenchymal Stem cells
Project IdMSK TO1_LF
Main solverprof. MUDr. Roman Hájek, CSc.
Period8/2016 - 12/2017
ProviderKatedra interních oborů, Projekty podporované z rozpočtu měst krajských úřadů
AnotationThe current project builds on input project "Zahájení dlouhodobého výzkumu u monoklonálních gamapatií" and will promote further development of applied and basic research at the Medical Faculty, University of Ostrava. We proposed to establish ?myeloma-in-dish? 3D model together with application of Induced Pluripotent Stem Cells (iPSCs) technology. The aim is to generate in vitro bone marrow microenvironment model based on multiple components and growth factors in the presence of mesenchymal cell to explore new avenue towards the drug development.