Projects & Grants

Internal Grant Competition DGC
START-UP grant

Therapeutic monitoring of natalizumabe in patients with multiple sclerosis
Project IdSGS19/LF/2023
Main solverPharmDr. Denisa MOŠKOŘOVÁ
Period1/2023 - 12/2023
ProviderSpecifický VŠ výzkum
AnotationNatalizumab is a monoclonal antibody for treatment of multiple sclerosis. It belongs among the disease modifying drugs a group of so-called big molecules. The aim of this project is correlation of natalizumab serum concentrations with clinical conditions of patients (EDSS scale, no of relapses, magnetic resonance outcomes) as well as correlation with adverse drug reactions. The main goal of the project will be to optimize the therapy of multiple sclerosis in the efficacy of treatment and of course the treatment side effects with the aid of therapeutic drug monitoring.