Projects & Grants

Internal Grant Competition DGC





Comparison of internal carotid stenosis evaluation using modern imaging methods with creation of optimal evaluation algorithm for duplex sonography
Project IdSGS18/LF/2022
Main solverDavid Pakizer
Period1/2022 - 12/2022
ProviderSpecifický VŠ výzkum
Statesolved
AnotationAtherosclerosis and its complications cause about 50% of deaths. Carotid bifurcation is the most common site of atherosclerotic plaque and subsequent hemodynamic stenosis, with carotid bifurcation stenosis being one of the most common causes of ischemic stroke. Extracranial carotid artery stenosis is responsible for approximately one-third of all strokes. If the stenosis is greater than 50% in symptomatic patients or greater than 70% in asymptomatic patients, according to current criteria, an interventional management of stenosis (surgical carotid endarterectomy or intraluminal carotid angioplasty with a stent) should follow. Because the various diagnostic methods of carotid stenosis use different physical principles, the agreement in the assessment of severity between the individual methods is still relatively low. The aim of the project is to compare the evaluation of internal carotid artery stenosis using ultrasound (B image - NASCET and ECST measurement techniques; duplex sonography - maximum flow rate and flow rate ratio), magnetic resonance and computed tomography (using the NASCET method) according to the latest criteria and subsequently creating optimal stenosis evaluation algorithm.