Projects & Grants

Internal Grant Competition DGC





Host proteins of Leishmania guyanensis involved in Leishmania RNA virus 1 maintenance
Project Id
Main solverMgr. Alexandra Zakharova
Period9/2021 - 2/2023
ProviderKatedra biologie a ekologie, DGC
Statesolved
AnotationEndogenous Leishmania RNA virus 1 (LRV1) of Leishmania guyanensis has been shown to facilitate pathogen's spread and be associated with the drug treatment failures of mucocutaneous Leishmania infection. Therefore, studies of LRV1 are potentially important from the medical perspective. In this project we plan to perform an analysis of the host proteins interacting with LRV1. They will be analyzed and tested in vitro and in vivo for their putative role in LRV1 maintenance.